Agatha Christie

 dyslexic

 William Hewlett

 dyslexic

 Nolan Ryan

 dyslexic

 Harrison Ford

 dyslexic

 Jackie Stewart

 dyslexic

 Danny Glover

 dyslexic

 Jay Leno

 dyslexic

 Cher

 dyslexic

 George Burns

 dyslexic

 Walt Disney

 dyslexic

 Nelson Rockefeller

 dyslexic

 Whopi Goldberg

 dyslexic

 Albert Einstein

 dyslexic

 Leonardo da Vinci

 dyslexic

 Tom Cruise

 dyslexic

 Thomas Edison

 dyslexia, deaf

 Sir Winston Churchill 

 bipolar

 Jim Abbott

 one handed

 Lucille Ball 

 rheumatoid arthritis

John F. Kennedy 

 war injuries

 Itzak Perlman

 polio

 Wilma Rudolph

 partially paralyzed